IgG4 Levels in Bile for Distinguishing IgG4-Associated Cholangiopathy from Other Biliary Disorders: A Single Blinded Pilot Study
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چکیده
منابع مشابه
IgG4 Levels in Bile for Distinguishing IgG4-Associated Cholangiopathy from Other Biliary Disorders: A Single Blinded Pilot Study
BACKGROUND/AIMS Immunoglobulin G4 (IgG4)-associated cholangiopathy (IAC) is an inflammatory disease and may mimic primary sclerosing cholangitis (PSC), cholangiocarcinoma (CCA), or pancreatic cancer on cholangiography. We investigated whether IgG4 levels in bile aspirated during endoscopic retrograde cholangiopancreatography (ERCP) can distinguish IAC from PSC, CCA, and pancreatic cancer. MET...
متن کاملIgG4 Cholangiopathy
IgG4 cholangiopathy can involve any level of the biliary tree which exhibits sclerosing cholangitis or pseudotumorous hilar lesions. Most cases are associated with autoimmune pancreatitis, an important diagnostic clue. Without autoimmune pancreatitis, however, the diagnosis of IgG4-cholangiopathy is challenging. Indeed such cases have been treated surgically. IgG4-cholangiopathy should be diagn...
متن کاملDetection of Serum IgG4 Levels in Patients with IgG4-Related Disease and Other Disorders
OBJECTIVE Elevated serum IgG4 levels are an important hallmark for diagnosing IgG4-related disease (IgG4-RD), but can also be observed in other diseases. This study aimed to compare two different testing methods for IgG4: ELISA and nephelometric assay. Both assays were used to measure serum IgG4 concentrations, and to assess the prevalence of high serum IgG4 levels in both IgG4-RD and non-IgG4-...
متن کاملSequential Evaluation of Pancreato-Biliary Findings in a Case with IgG4-Associated Cholangiopathy and Autoimmune Pancreatitis during Corticosteroid Treatment.
BACKGROUND Immunoglobulin G4 (IgG4)-associated diseases mostly involve the pancreaticobiliary tree and pancreatic parenchyma. This disease complex is characterized by marked response to corticosteroid therapy and response to steroids is incorporated in the diagnostic algorithm of IgG4 associated diseases. However, there is much unknown about the sequences and duration of healing during the cort...
متن کاملویژگی ها IgG4 و بیماری های مرتبط با IgG4
Abstract Background: In the serum of healthy people, IgG4 has lowest concentration among the different sub-classes of IgG. Elevation of serum IgG4 in response to chronic antigenic stimulation and inflammation has been reported. Inflammation, histopathologic lesions and systemic organ involvement have been reported in the IgG4-related disease (IgG4-RD). In this article we review IgG4 unique f...
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ژورنال
عنوان ژورنال: Clinical Endoscopy
سال: 2014
ISSN: 2234-2400,2234-2443
DOI: 10.5946/ce.2014.47.6.555